Therapeutic options here are based on EMA drug approvals with deviating approval details clearly marked. Drugs availability may vary in your country.


BRAF – Protein Kinase B-Rapidly Accelerated Fibrosarcoma
BTC – Biliary Tract Cancer
CCA – Cholangiocarcinoma
CNA – Copy Number Amplifications
CPS – Combined Positive Score
EMA – European Medicines Agency
ERBB – Erb-B2 Receptor Tyrosine Kinase; Avian Erythroblastic Leukemia Viral Oncogene Homolog
ERK – alias: MAPK1 - Mitogen-Activated Protein Kinase 1
FDA – Food and Drug Administration
FFPE – Formalin-Fixed Paraffin-Embedded (tissue)
FGF – Fibroblast Growth Factor
FGFR – Fibroblast Growth Factor Receptor
FISH – Fluorescence In Situ Hybridization
HER2 – Human Epidermal Receptor 2
IC – Immune Cell
IDH – Isocitrate Dehydrogenase
IHC – Immunohistochemistry
KRAS – Kirsten Rat Sarcoma Viral Oncogene
MAPK – Mitogen-Activated Protein Kinase
MEK – alias: MAP2K1 - Mitogen-Activated Protein Kinase Kinase 1
MMR – Mismatch Repair
MSI – Microsatellite Instability
NGS – Next Generation Sequencing
NTRK – Neurotrophic Receptor Tyrosine Kinase
PCR – Polymerase Chain Reaction
PD-L1 – Programmed Cell Death Ligand 1
QuIP – Qualitätssicherungs-Initiative Pathologie QuIP GmbH
RTK – Receptor Tyrosine Kinase
SNVs – Single-Nucleotide Variants
SOP – Standard Operating Procedure
TCA – Tricarboxylic Acid
UBC – Urothelial Bladder C